{"id":689,"date":"2026-01-31T09:21:15","date_gmt":"2026-01-31T09:21:15","guid":{"rendered":"https:\/\/madinslovenia.org\/?p=689"},"modified":"2026-04-09T12:54:08","modified_gmt":"2026-04-09T12:54:08","slug":"teorija-kemicnega-neravnovesja-pri-depresiji-urbana-legenda-ki-vztraja","status":"publish","type":"post","link":"https:\/\/madinslovenia.org\/?p=689","title":{"rendered":"Teorija kemi\u010dnega neravnovesja pri depresiji: urbana legenda,\u00a0ki vztraja\u00a0"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\">Kratek komentar\u00a0Dawsona\u00a0in\u00a0Piesa\u00a0je odziv na \u010dlanek\u00a0Anga\u00a0in sodelavcev\u00a0(Ang, B.,\u00a0Horowitz, M., &amp;\u00a0Moncrieff, J. 2022.\u00a0Is\u00a0the\u00a0chemical\u00a0imbalance\u00a0an\u00a0\u2018urban legend\u2019? An\u00a0exploration\u00a0of\u00a0the\u00a0status\u00a0of\u00a0the\u00a0serotonin\u00a0theory\u00a0of\u00a0depression\u00a0in\u00a0the\u00a0scientific\u00a0literature).\u00a0Avtorja\u00a0trdita,\u00a0da akademska psihiatrija nikoli ni zagovarjala poenostavljene teorije kemi\u010dnega neravnovesja pri depresiji.\u00a0Navajata, da je v obdobju 1990-2010 obstajalo vsaj 17 drugih hipotez o depresiji.\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Mnogi v javnosti verjamejo, da depresijo povzro\u010da pomanjkanje serotonina v mo\u017eganih in da antidepresivi to neravnovesje odpravijo.&nbsp;Ta razlaga je preprosta in privla\u010dna, vendar ni skladna z znanstvenimi dejstvi. Avtorja poudarjata, da farmakologi in psihiatri \u017ee ve\u010d desetletij vedo, da depresija ni preprosto posledica pomanjkanja serotonina.&nbsp;Vzroki depresije so kompleksni in vklju\u010dujejo genetske predispozicije, stres, vnetja, spremembe v mo\u017eganskih vezjih ter \u0161tevilne druge biolo\u0161ke, psiholo\u0161ke in socialne dejavnike.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Antidepresivi, kot so selektivni zaviralci ponovnega privzema serotonina, ne \u00bbpopravljajo\u00ab kemi\u010dnega neravnovesja, njihov na\u010din delovanja je veliko bolj zapleten in \u0161e vedno ni povsem razumljen.&nbsp;&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Avtorja navajata, da poenostavljena razlaga izvira predvsem iz tr\u017enega&nbsp;ogla\u0161evanja&nbsp;zdravil&nbsp;(npr.&nbsp;reklam&nbsp;za&nbsp;Zoloft), ne pa iz akademske psihiatrije.&nbsp;Napa\u010dna razlaga&nbsp;se&nbsp;v javnosti ohranja zaradi poenostavljenih medicinskih razlag, marketin\u0161kih kampanj ter potrebe javnosti po preprostih odgovorih na zapletena vpra\u0161anja.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Avtorja poudarjata, da ameri\u0161ka akademska psihiatrija \u017ee ve\u010d kot 40 let uporablja&nbsp;biopsihosocialni&nbsp;model, ki razume psihiatri\u010dne motnje kot rezultat kompleksne interakcije fizi\u010dnih, psiholo\u0161kih in socialnih dejavnikov.&nbsp;Ameri\u0161ko psihiatri\u010dno zdru\u017eenje je \u017ee leta 1978 poudarilo, da mora zdravljenje psihiatri\u010dnih motenj upo\u0161tevati fizi\u010dne, psiholo\u0161ke in socialne dejavnike, bodisi posami\u010dno bodisi hkrati.&nbsp;<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">Vir:\u00a0Dawson, G., &amp; Pies, R. W. (2022). An &#8216;urban legend&#8217;\u00a0remains\u00a0an &#8216;urban legend&#8217;.\u00a0SSM &#8211; Mental Health,\u00a02, 100133.\u00a0<a href=\"https:\/\/doi.org\/10.1016\/j.ssmmh.2022.100133\" target=\"_blank\" rel=\"noreferrer noopener\">https:\/\/doi.org\/10.1016\/j.ssmmh.2022.100133<\/a>\u00a0<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Kratek komentar\u00a0Dawsona\u00a0in\u00a0Piesa\u00a0je odziv na \u010dlanek\u00a0Anga\u00a0in sodelavcev\u00a0(Ang, B.,\u00a0Horowitz, M., &amp;\u00a0Moncrieff, J. 2022.\u00a0Is\u00a0the\u00a0chemical\u00a0imbalance\u00a0an\u00a0\u2018urban legend\u2019? An\u00a0exploration\u00a0of\u00a0the\u00a0status\u00a0of\u00a0the\u00a0serotonin\u00a0theory\u00a0of\u00a0depression\u00a0in\u00a0the\u00a0scientific\u00a0literature).\u00a0Avtorja\u00a0trdita,\u00a0da akademska psihiatrija nikoli ni zagovarjala poenostavljene teorije kemi\u010dnega neravnovesja pri depresiji.\u00a0Navajata, da je v obdobju 1990-2010 obstajalo vsaj 17 drugih hipotez o depresiji.\u00a0 Mnogi v javnosti verjamejo, da depresijo povzro\u010da pomanjkanje serotonina v mo\u017eganih in da antidepresivi to neravnovesje odpravijo.&nbsp;Ta razlaga je [&hellip;]<\/p>\n","protected":false},"author":20,"featured_media":691,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[7],"tags":[],"class_list":["post-689","post","type-post","status-publish","format-standard","has-post-thumbnail","category-strokovni-prispevki"],"_links":{"self":[{"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/posts\/689","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/users\/20"}],"replies":[{"embeddable":true,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=689"}],"version-history":[{"count":1,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/posts\/689\/revisions"}],"predecessor-version":[{"id":692,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/posts\/689\/revisions\/692"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=\/wp\/v2\/media\/691"}],"wp:attachment":[{"href":"https:\/\/madinslovenia.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=689"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=689"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/madinslovenia.org\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=689"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}